diff --git a/mediapipe/framework/api2/node.h b/mediapipe/framework/api2/node.h
index 7061afcae..14c098246 100644
--- a/mediapipe/framework/api2/node.h
+++ b/mediapipe/framework/api2/node.h
@@ -88,7 +88,8 @@ struct NodeRegistrationStatic {
   static mediapipe::RegistrationToken Make() {
     return mediapipe::CalculatorBaseRegistry::Register(
         T::kCalculatorName,
-        absl::make_unique<mediapipe::internal::CalculatorBaseFactoryFor<T>>);
+        absl::make_unique<mediapipe::internal::CalculatorBaseFactoryFor<T>>,
+        __FILE__, __LINE__);
   }
 
   using RequireStatics = ForceStaticInstantiation<&registration>;
@@ -104,8 +105,8 @@ struct SubgraphRegistrationImpl {
   static NoDestructor<mediapipe::RegistrationToken> registration;
 
   static mediapipe::RegistrationToken Make() {
-    return mediapipe::SubgraphRegistry::Register(T::kCalculatorName,
-                                                 absl::make_unique<T>);
+    return mediapipe::SubgraphRegistry::Register(
+        T::kCalculatorName, absl::make_unique<T>, __FILE__, __LINE__);
   }
 
   using RequireStatics = ForceStaticInstantiation<&registration>;
@@ -223,12 +224,13 @@ class SubgraphImpl : public Subgraph, public Intf {
 
 // This macro is used to register a calculator that does not use automatic
 // registration. Deprecated.
-#define MEDIAPIPE_NODE_IMPLEMENTATION(Impl)                                  \
-  static mediapipe::NoDestructor<mediapipe::RegistrationToken>               \
-  REGISTRY_STATIC_VAR(calculator_registration,                               \
-                      __LINE__)(mediapipe::CalculatorBaseRegistry::Register( \
-      Impl::kCalculatorName,                                                 \
-      absl::make_unique<mediapipe::internal::CalculatorBaseFactoryFor<Impl>>))
+#define MEDIAPIPE_NODE_IMPLEMENTATION(Impl)                                   \
+  static mediapipe::NoDestructor<mediapipe::RegistrationToken>                \
+  REGISTRY_STATIC_VAR(calculator_registration,                                \
+                      __LINE__)(mediapipe::CalculatorBaseRegistry::Register(  \
+      Impl::kCalculatorName,                                                  \
+      absl::make_unique<mediapipe::internal::CalculatorBaseFactoryFor<Impl>>, \
+      __FILE__, __LINE__))
 
 // This macro is used to register a non-split-contract calculator. Deprecated.
 #define MEDIAPIPE_REGISTER_NODE(name) REGISTER_CALCULATOR(name)
@@ -239,7 +241,7 @@ class SubgraphImpl : public Subgraph, public Intf {
   static mediapipe::NoDestructor<mediapipe::RegistrationToken>         \
   REGISTRY_STATIC_VAR(subgraph_registration,                           \
                       __LINE__)(mediapipe::SubgraphRegistry::Register( \
-      Impl::kCalculatorName, absl::make_unique<Impl>))
+      Impl::kCalculatorName, absl::make_unique<Impl>, __FILE__, __LINE__))
 
 }  // namespace api2
 }  // namespace mediapipe
diff --git a/mediapipe/framework/calculator_base_test.cc b/mediapipe/framework/calculator_base_test.cc
index 42c03696c..c26006e0f 100644
--- a/mediapipe/framework/calculator_base_test.cc
+++ b/mediapipe/framework/calculator_base_test.cc
@@ -183,7 +183,8 @@ TEST(CalculatorTest, CreateByNameWhitelisted) {
   CalculatorBaseRegistry::Register(
       "::mediapipe::test_ns::whitelisted_ns::DeadCalculator",
       absl::make_unique<internal::CalculatorBaseFactoryFor<
-          mediapipe::test_ns::whitelisted_ns::DeadCalculator>>);
+          mediapipe::test_ns::whitelisted_ns::DeadCalculator>>,
+      __FILE__, __LINE__);
 
   // A whitelisted calculator can be found in its own namespace.
   MP_EXPECT_OK(CalculatorBaseRegistry::CreateByNameInNamespace(  //
diff --git a/mediapipe/framework/deps/registration.h b/mediapipe/framework/deps/registration.h
index 9d80aafea..cc8ba03fe 100644
--- a/mediapipe/framework/deps/registration.h
+++ b/mediapipe/framework/deps/registration.h
@@ -16,6 +16,7 @@
 #define MEDIAPIPE_DEPS_REGISTRATION_H_
 
 #include <algorithm>
+#include <cstdint>
 #include <functional>
 #include <string>
 #include <tuple>
@@ -161,7 +162,8 @@ class FunctionRegistry {
   FunctionRegistry(const FunctionRegistry&) = delete;
   FunctionRegistry& operator=(const FunctionRegistry&) = delete;
 
-  RegistrationToken Register(absl::string_view name, Function func)
+  RegistrationToken Register(absl::string_view name, Function func,
+                             std::string filename, uint64_t line)
       ABSL_LOCKS_EXCLUDED(lock_) {
     std::string normalized_name = GetNormalizedName(name);
     absl::WriterMutexLock lock(&lock_);
@@ -171,10 +173,21 @@ class FunctionRegistry {
     }
     if (functions_.insert(std::make_pair(normalized_name, std::move(func)))
             .second) {
+#ifndef NDEBUG
+      locations_.emplace(normalized_name,
+                         std::make_pair(std::move(filename), line));
+#endif
       return RegistrationToken(
           [this, normalized_name]() { Unregister(normalized_name); });
     }
+#ifndef NDEBUG
+    LOG(FATAL) << "Function with name " << name << " already registered."
+               << " First registration at "
+               << locations_.at(normalized_name).first << ":"
+               << locations_.at(normalized_name).second;
+#else
     LOG(FATAL) << "Function with name " << name << " already registered.";
+#endif
     return RegistrationToken([]() {});
   }
 
@@ -291,6 +304,11 @@ class FunctionRegistry {
  private:
   mutable absl::Mutex lock_;
   absl::flat_hash_map<std::string, Function> functions_ ABSL_GUARDED_BY(lock_);
+#ifndef NDEBUG
+  // Stores filename and line number for useful debug log.
+  absl::flat_hash_map<std::string, std::pair<std::string, uint32_t>> locations_
+      ABSL_GUARDED_BY(lock_);
+#endif
 
   // For names included in NamespaceAllowlist, strips the namespace.
   std::string GetAdjustedName(absl::string_view name) {
@@ -321,8 +339,10 @@ class GlobalFactoryRegistry {
 
  public:
   static RegistrationToken Register(absl::string_view name,
-                                    typename Functions::Function func) {
-    return functions()->Register(name, std::move(func));
+                                    typename Functions::Function func,
+                                    std::string filename, uint64_t line) {
+    return functions()->Register(name, std::move(func), std::move(filename),
+                                 line);
   }
 
   // Invokes the specified factory function and returns the result.
@@ -382,12 +402,12 @@ class GlobalFactoryRegistry {
 #define MEDIAPIPE_REGISTER_FACTORY_FUNCTION(RegistryType, name, ...) \
   static auto* REGISTRY_STATIC_VAR(registration_##name, __LINE__) =  \
       new mediapipe::RegistrationToken(                              \
-          RegistryType::Register(#name, __VA_ARGS__))
+          RegistryType::Register(#name, __VA_ARGS__, __FILE__, __LINE__))
 
 #define REGISTER_FACTORY_FUNCTION_QUALIFIED(RegistryType, var_name, name, ...) \
   static auto* REGISTRY_STATIC_VAR(var_name, __LINE__) =                       \
       new mediapipe::RegistrationToken(                                        \
-          RegistryType::Register(#name, __VA_ARGS__))
+          RegistryType::Register(#name, __VA_ARGS__, __FILE__, __LINE__))
 
 }  // namespace mediapipe
 
diff --git a/mediapipe/framework/packet.h b/mediapipe/framework/packet.h
index 1024cbc15..af2ec5a98 100644
--- a/mediapipe/framework/packet.h
+++ b/mediapipe/framework/packet.h
@@ -466,7 +466,8 @@ struct MessageRegistrationImpl {
 template <typename T>
 NoDestructor<mediapipe::RegistrationToken>
     MessageRegistrationImpl<T>::registration(MessageHolderRegistry::Register(
-        T{}.GetTypeName(), MessageRegistrationImpl<T>::CreateMessageHolder));
+        T{}.GetTypeName(), MessageRegistrationImpl<T>::CreateMessageHolder,
+        __FILE__, __LINE__));
 
 // For non-Message payloads, this does nothing.
 template <typename T, typename Enable = void>
diff --git a/mediapipe/framework/subgraph.cc b/mediapipe/framework/subgraph.cc
index 7cbde28bf..6c18c9cac 100644
--- a/mediapipe/framework/subgraph.cc
+++ b/mediapipe/framework/subgraph.cc
@@ -64,13 +64,13 @@ GraphRegistry::GraphRegistry(
 void GraphRegistry::Register(
     const std::string& type_name,
     std::function<std::unique_ptr<Subgraph>()> factory) {
-  local_factories_.Register(type_name, factory);
+  local_factories_.Register(type_name, factory, __FILE__, __LINE__);
 }
 
 // TODO: Remove this convenience function.
 void GraphRegistry::Register(const std::string& type_name,
                              const CalculatorGraphConfig& config) {
-  local_factories_.Register(type_name, [config] {
+  Register(type_name, [config] {
     auto result = absl::make_unique<ProtoSubgraph>(config);
     return std::unique_ptr<Subgraph>(result.release());
   });
@@ -79,7 +79,7 @@ void GraphRegistry::Register(const std::string& type_name,
 // TODO: Remove this convenience function.
 void GraphRegistry::Register(const std::string& type_name,
                              const CalculatorGraphTemplate& templ) {
-  local_factories_.Register(type_name, [templ] {
+  Register(type_name, [templ] {
     auto result = absl::make_unique<TemplateSubgraph>(templ);
     return std::unique_ptr<Subgraph>(result.release());
   });